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Multidimensional and
comprehensive separations
Multidimensional
separations involve taking the species that are eluted from one
chromatographic system and then separating them on another
chromatographic system, which has different separation selectivity.
When all of the output form the first separation system is
passed to the second system (rather than just selected parts of the
first output), then the resultant separation is termed
"comprehensive". Australia is recognised internationally for research in
comprehensive separations conducted in the gas phase (GCxGC), primarily
as a result of research conducted at RMIT.
New hardware for GCxGC has been patented and commercialised and
has been applied to a wide range of very complex samples. Development of comprehensive liquid phase separation systems
is an important goal for Australian research.
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